Congenital Defects due to Thalidomide
نویسندگان
چکیده
منابع مشابه
Recognition of thalidomide defects.
Thalidomide: a brief history Thalidomide (alpha-phthalimido-glutarimide) was developed by the German firm Chemie Grunenthal as an anticonvulsant drug. Early trials showed it to be unsuitable for this purpose but indicated that it had sedative properties. Furthermore, it had one remarkable property: overdoses simply caused prolonged sleep, not death. The drug was first marketed in Germany in 195...
متن کاملOcular Defects in Thalidomide Babies.
IN the early reports on congenital abnormalities in thalidomide babies in Great Britain little attention has been paid to the occurrence of ocular defects. A recent survey by the Chief Medical Officer of the Ministry of Health relating to children born with congenital limb deformities during 1960-62, revealed that there were 652 surviving children with such deformities, 244 of whose mothers had...
متن کاملBeyond Thalidomide - Birth Defects Explained
This book will appeal to the student of medical history and would be of interest to those entering general practice to obtain some insight into how their specialty evolved in modern times. The book is well written and scholarly and gives the reader a real sense of the evolutionary processes affecting general practice in the mid twentieth century with the foundation of the College of General Pra...
متن کاملHypothyroidism due to enzyme defects.
Defects in thyroid hormone production, transport and utilization are classified. Particular attention is given to inherited intrathyroidal defects in hormone synthesis which impair thyroid function and lead to goitre formation and hypothyroidism. Anomalies in biosynthesis may also result from disease or drugs. Reference is made to the derangement of iodine metabolism that results from iodine de...
متن کاملCongenital entropion due to epiblepharon.
CONGENITAL entropion is a rare malformation of the eyelid and for that reason this case is worth publishing. Among the 160,000 patients of the University Eye Clinic Debrecen in the last 25 years many cases of epiblepharon have been observed, but among them this is the only one in which we had to deal with real entropion.
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ژورنال
عنوان ژورنال: BMJ
سال: 1963
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5323.123